Resistant target!
They sure are sneaky little things. This is just one example of how bacteria can resist antibiotics. Read more in one of my favorite articles:
Reygaert (2018) “An overview of the antimicrobial resistance mechanisms of bacteria” https://doi.org/10.3934/microbiol.2018.3.482 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604941/